Rooted in Cambridge. United by a global ambition
A new possibility for medicine
A shared purpose to advance it
What could become possible if we could restore the function of cells affected by disease?
RESTORE brings people and organisations together to explore that possibility, combining their expertise to advance restoration therapeutics.
Why we exist
The possibility matters because people do
Behind every therapeutic ambition are people hoping for better treatments, greater independence and more time living well.
Restoration therapeutics explores the possibility of recovering cellular function impaired by disease. Realising its promise will require discoveries, rigorous evidence and capabilities that span many disciplines.
We believe progress becomes possible when people unite around that purpose and bring their different strengths to it.
Our mission is to make Cambridge a global centre of excellence and collaboration, advancing restoration therapeutics for people everywhere.
Three pillars
How we turn purpose into progress
01
Align the mission
Start with a question worth answering and an outcome people care about. Find the shared purpose that gives different organisations a reason to work together.
02
Bring the strengths
Connect people whose expertise complements one another. Give each contributor a clear role and the opportunity to do what they do best.
03
Build together
Turn that alignment into joint programmes, with clear responsibilities, meaningful milestones and learning that informs the next step.
Different strengths. Shared purpose
You do not have to build every capability to make a meaningful contribution
One team may understand the biology. Another may have the model needed to test it. Others bring the technology, data or experience needed to move a promising idea towards therapeutic development.
The opportunity lies in bringing those strengths together around a mission each contributor has a reason to advance.
RESTORE exists to help those collaborations take shape and develop into sustained work.
The approach we are building
- Find the question that matters
- Align around a shared outcome
- Bring complementary expertise together
- Define the work and carry it forward
Where collaboration can make a difference
Important questions deserve a shared effort
How do we understand the cellular changes that drive disease? How do we test whether restoring function could make a meaningful difference? What evidence would help a promising approach move towards patients?
These are the kinds of questions around which we want to bring collaborators together.
Opportunities for joint work
Understand cellular state
Explore how the mechanisms that regulate cell behaviour relate to function, age and disease, and where opportunities for restoration may exist.
Build better ways to test
Combine biological insight with disease-relevant models and measurement tools to investigate whether an intervention restores meaningful function.
Connect discovery with development
Bring scientific, technological and translational expertise together to identify the evidence and capabilities a potential therapy will need.
These areas describe opportunities for collaboration. Individual programmes will be introduced as their scope and contributors are confirmed.
Foundations for a growing field
Some questions are bigger than any one programme
A map of the regulatory changes associated with disease. A model that helps researchers ask better questions. A shared way to measure whether cellular function has improved.
Work like this can support many discoveries and many organisations. It needs a shared ambition that connects scientific curiosity, commercial possibility and therapeutic purpose.
RESTORE aims to bring contributors together around these foundational challenges, helping build knowledge that the wider field can use.
Conceptual illustration of cellular systems
Bring your part
What could we make possible together?
You may have a question that needs another discipline, a capability that could unlock someone else’s work, or an ambition that requires partners to pursue it.
We would like to hear from you.
RESTORE is being built for people and organisations who share a commitment to advancing restoration therapeutics and see the value of contributing their strengths to a common purpose.
We welcome contributions from
- Academic research
- Biotechnology and pharmaceutical development
- Disease models and enabling technologies
- Data science and AI
- Clinical and translational expertise
- Funding and other enabling organisations